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Literature summary extracted from

  • Sak, A.; Fegers, I.; Groneberg, M.; Stuschke, M.
    Effect of separase depletion on ionizing radiation-induced cell cycle checkpoints and survival in human lung cancer cell lines (2008), Cell Prolif., 41, 660-670.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.22.49 depletion of endogenous separase with siRNA in NSCLCs shows that separase affects progression through the G2 phase of mitosis. Analysis of the effect of separase depletion on irradiated cells (cell cycle progression, M-phase fraction, late mitotic-linked cell death and clonogenic survival) Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.49 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.49 non-small cell lung cancer cell line
-
Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
3.4.22.49 separase
-
Homo sapiens